5XA1
Crystal structure of inositol 1,4,5-trisphosphate receptor cytosolic domain with inositol 1,4,5-trisphosphate
Summary for 5XA1
Entry DOI | 10.2210/pdb5xa1/pdb |
Related | 5X9Z 5XA1 |
Descriptor | Inositol 1,4,5-trisphosphate receptor type 1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (2 entities in total) |
Functional Keywords | receptor channel calcium, metal transport |
Biological source | Mus musculus (Mouse) |
Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : P11881 |
Total number of polymer chains | 2 |
Total formula weight | 362855.19 |
Authors | Hamada, K.,Miyatake, H.,Terauchi, A.,Mikoshiba, K. (deposition date: 2017-03-10, release date: 2017-04-19, Last modification date: 2023-11-22) |
Primary citation | Hamada, K.,Miyatake, H.,Terauchi, A.,Mikoshiba, K. IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography Proc. Natl. Acad. Sci. U.S.A., 114:4661-4666, 2017 Cited by PubMed: 28416699DOI: 10.1073/pnas.1701420114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.204 Å) |
Structure validation
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