5X8W
Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.
Summary for 5X8W
Entry DOI | 10.2210/pdb5x8w/pdb |
Related | 5X8Q 5X8S 5X8U 5X8X |
Descriptor | Nuclear receptor ROR-gamma, Nuclear receptor coactivator 1 (3 entities in total) |
Functional Keywords | inhibitor, binary complex, nuclear receptor, transcription-inhibitor complex, transcription/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 31530.37 |
Authors | Noguchi, M.,Nomura, A.,Murase, K.,Doi, S.,Yamaguchi, K.,Adachi, T. (deposition date: 2017-03-03, release date: 2017-06-07, Last modification date: 2023-11-22) |
Primary citation | Noguchi, M.,Nomura, A.,Murase, K.,Doi, S.,Yamaguchi, K.,Hirata, K.,Shiozaki, M.,Hirashima, S.,Kotoku, M.,Yamaguchi, T.,Katsuda, Y.,Steensma, R.,Li, X.,Tao, H.,Tse, B.,Fenn, M.,Babine, R.,Bradley, E.,Crowe, P.,Thacher, S.,Adachi, T.,Kamada, M. Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment Genes Cells, 22:535-551, 2017 Cited by PubMed: 28493531DOI: 10.1111/gtc.12494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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