5X8W
Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 258 | 29754.3 | 1 | UniProt (P51449) Pfam (PF00104) UniProt (by SIFTS) (G1RH57) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 15 | 1776.1 | 1 | UniProt (Q15788) | Homo sapiens (Human) | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | C, D (A, B) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A: 261 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Ala 469 | Lys 469 | engineered mutation |
| Ala 473 | Arg 473 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31530.4 | |
| All* | Total formula weight | 31530.4 |
