5X68
Crystal Structure of Human KMO
Summary for 5X68
Entry DOI | 10.2210/pdb5x68/pdb |
Related | 5X6P 5X6Q 5X6R |
Descriptor | Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | monooxygenase, flavin reduction, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion outer membrane ; Multi-pass membrane protein : O15229 |
Total number of polymer chains | 2 |
Total formula weight | 90141.34 |
Authors | Kim, H.T.,Hwang, K.Y. (deposition date: 2017-02-21, release date: 2018-02-21, Last modification date: 2018-05-02) |
Primary citation | Kim, H.T.,Na, B.K.,Chung, J.,Kim, S.,Kwon, S.K.,Cha, H.,Son, J.,Cho, J.M.,Hwang, K.Y. Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25:426-438.e4, 2018 Cited by PubMed: 29429898DOI: 10.1016/j.chembiol.2018.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report