5WY0

Crystal structure of the methyltranferase domain of human HEN1 in complex with AdoMet

5WY0 の概要

• エントリーDOI: 10.2210/pdb5wy0/pdb
• 分子名称: Small RNA 2'-O-methyltransferase, S-ADENOSYLMETHIONINE (3 entities in total)
• 機能のキーワード: rna methyltranferase, adomet, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26520.98

構造登録者

Peng, L.,Ma, J.B.,Wu, L.G.,Huang, Y. (登録日: 2017-01-10, 公開日: 2018-01-17, 最終更新日: 2024-03-20)

• 主引用文献: Peng, L.,Zhang, F.,Shang, R.,Wang, X.,Chen, J.,Chou, J.J.,Ma, J.,Wu, L.,Huang, Y.; Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain; J. Biol. Chem., 293:9981-9994, 2018; PubMed: 29703750; DOI: 10.1074/jbc.RA117.000837

実験手法

X-RAY DIFFRACTION (2.001 Å)