5WX1

The closed-conformation crystal structure of the full-length pestivirus NS3 with its NS4A protease cofactor segment

Summary for 5WX1

Entry DOI	10.2210/pdb5wx1/pdb
Descriptor	Serine protease NS3 (2 entities in total)
Functional Keywords	protease, rna helicase, hydrolase
Biological source	Classical swine fever virus
Cellular location	Virion : Q5U8X5
Total number of polymer chains	1
Total formula weight	81537.04
Authors	Zheng, F.,Lu, G.,Gong, P. (deposition date: 2017-01-06, release date: 2017-08-23, Last modification date: 2023-11-22)
Primary citation	Zheng, F.,Lu, G.,Li, L.,Gong, P.,Pan, Z. Uncoupling of Protease trans-Cleavage and Helicase Activities in Pestivirus NS3. J. Virol., 91:-, 2017 Cited by PubMed: 28835495 DOI: 10.1128/JVI.01094-17 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation