5WPK

Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to HMG-CoA and in a partially closed conformation

5WPK の概要

• エントリーDOI: 10.2210/pdb5wpk/pdb
• 分子名称: 3-hydroxy-3-methylglutaryl coenzyme A reductase, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: 3-hydroxy-3-methylglutaryl-coa reductase, hmg-coa, conformational change, oxidoreductase
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 95714.03

構造登録者

Miller, B.R.,Kung, Y. (登録日: 2017-08-04, 公開日: 2018-04-25, 最終更新日: 2023-10-04)

• 主引用文献: Miller, B.R.,Kung, Y.; Structural Features and Domain Movements Controlling Substrate Binding and Cofactor Specificity in Class II HMG-CoA Reductase.; Biochemistry, 57:654-662, 2018; PubMed: 29224355; DOI: 10.1021/acs.biochem.7b00999

実験手法

X-RAY DIFFRACTION (2.3 Å)