5WM1

Structure of the 10S (+)-trans-BP-dG modified Rev1 ternary complex

Summary for 5WM1

• Entry DOI: 10.2210/pdb5wm1/pdb
• Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*(DDG))-3'), DNA (5'-D(P*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA repair protein REV1, ... (10 entities in total)
• Functional Keywords: benzo[a]pyrene rev1 polymerase carcinogen lesion bypass, dna binding protein, transferase-dna complex, transferase/dna
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 3
• Total formula weight: 60220.57

Authors

Rechkoblit, O.,Kolbanovsky, A.,Landes, H.,Geacintov, N.E.,Aggarwal, A.K. (deposition date: 2017-07-28, release date: 2017-10-25, Last modification date: 2023-10-04)

• Primary citation: Rechkoblit, O.,Kolbanovskiy, A.,Landes, H.,Geacintov, N.E.,Aggarwal, A.K.; Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.; Nat Commun, 8:965-965, 2017; PubMed: 29042535; DOI: 10.1038/s41467-017-01013-5

Experimental method

X-RAY DIFFRACTION (1.85 Å)