5WM1

Structure of the 10S (+)-trans-BP-dG modified Rev1 ternary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG P 101

Chain	Residue
A	ASP548
A	LEU550
A	VAL553
A	HOH915
P	DA11
P	HOH212

---

site_id	AC2
Number of Residues	6
Details	binding site for residue BAP T 101

Chain	Residue
T	DG5
T	EDO102
T	HOH203
A	HIS555
A	MET685
P	DG2

---

site_id	AC3
Number of Residues	3
Details	binding site for residue EDO T 102

Chain	Residue
P	DG2
T	DG5
T	BAP101

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MG A 801

Chain	Residue
A	ASP362
A	SER465
A	ASP467
A	GLU468
A	MG802
A	DCP804
P	DDG12

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG A 802

Chain	Residue
A	ASP362
A	PHE363
A	ASP467
A	MG801
A	MG803
A	DCP804

---

site_id	AC6
Number of Residues	7
Details	binding site for residue MG A 803

Chain	Residue
A	ASP362
A	LYS525
A	MG802
A	DCP804
A	HOH1001
A	HOH1115
A	HOH1150

---

site_id	AC7
Number of Residues	26
Details	binding site for residue DCP A 804

Chain	Residue
A	ARG324
A	LEU328
A	ASP362
A	PHE363
A	ASP364
A	CYS365
A	PHE366
A	PHE367
A	ALA401
A	SER402
A	TYR405
A	ARG408
A	ASN414
A	ASP467
A	LYS525
A	MG801
A	MG802
A	MG803
A	HOH989
A	HOH1021
A	HOH1047
A	HOH1068
A	HOH1069
A	HOH1115
A	HOH1118
P	DDG12

---

site_id	AC8
Number of Residues	6
Details	binding site for residue GOL A 805

Chain	Residue
A	TYR356
A	ASP512
A	LYS534
A	HOH1033
A	HOH1056
A	HOH1079

---

site_id	AC9
Number of Residues	7
Details	binding site for residue GOL A 806

Chain	Residue
A	ARG494
A	GLN495
A	THR505
A	ASN527
A	HOH904
A	HOH907
A	HOH1017

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL A 807

Chain	Residue
A	ASP399
A	TRP417
A	LYS681
A	HOH943
A	HOH955
P	DG2
T	DG5

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL A 808

Chain	Residue
A	LEU335
A	PHE339
A	GLU342
A	ILE461
A	HOH903
A	HOH1012

---

site_id	AD3
Number of Residues	10
Details	binding site for residue GOL A 809

Chain	Residue
A	ILE457
A	ASN459
A	ARG473
A	ILE474
A	SER543
A	SER570
A	ASN572
A	ASP573
A	LYS576
A	HOH948

---

site_id	AD4
Number of Residues	2
Details	binding site for residue EDO A 810

Chain	Residue
A	SER544
A	ASP549

---

site_id	AD5
Number of Residues	2
Details	binding site for residue EDO A 811

Chain	Residue
A	THR351
A	ASP352

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO A 812

Chain	Residue
A	TRP331
A	ASN334
A	LYS338
A	HOH1025

---

site_id	AD7
Number of Residues	3
Details	binding site for residue EDO A 813

Chain	Residue
A	THR482
A	ASP512
A	HOH911

---

site_id	AD8
Number of Residues	6
Details	binding site for residue EDO A 814

Chain	Residue
A	CYS365
A	PHE384
A	HOH952
A	HOH971
A	HOH977
A	HOH1059

---

site_id	AD9
Number of Residues	4
Details	binding site for residue EDO A 815

Chain	Residue
A	PHE498
A	GLN499
A	ASN502
A	HOH1060

---

site_id	AE1
Number of Residues	5
Details	binding site for residue EDO A 816

Chain	Residue
A	VAL308
A	SER318
A	TYR319
A	HOH1106
T	DC4

---

site_id	AE2
Number of Residues	5
Details	binding site for residue PEG A 817

Chain	Residue
A	ASP566
A	SER695
A	ARG696
A	GLU710
A	HOH929

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	196
Details	Domain: {"description":"UmuC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00216","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	23
Details	Region: {"description":"Interaction with target DNA"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Active site: {"evidences":[{"source":"PubMed","id":"21167175","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16195463","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18275815","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21167175","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AQ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OSP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00216","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16195463","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18275815","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21167175","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AQ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OSP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18275815","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21167175","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OSP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16195463","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21167175","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AQ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OSP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Site: {"description":"Interaction with target DNA"}

Chain

Residue

Details

---