5WHD
Crystal structure of KRas G12V/D38P, bound to GDP
Summary for 5WHD
Entry DOI | 10.2210/pdb5whd/pdb |
Related | 5KLJ |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | open conformation of ras, gtp binding protein, protein binding |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116 |
Total number of polymer chains | 4 |
Total formula weight | 78319.20 |
Authors | Shim, S.Y.,McGee, J.H.,Lee, S.-J.,Verdine, G.L. (deposition date: 2017-07-16, release date: 2018-01-03, Last modification date: 2023-10-04) |
Primary citation | McGee, J.H.,Shim, S.Y.,Lee, S.J.,Swanson, P.K.,Jiang, S.Y.,Durney, M.A.,Verdine, G.L. Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293:3265-3280, 2018 Cited by PubMed: 29282294DOI: 10.1074/jbc.M117.816348 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.641 Å) |
Structure validation
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