Summary for 5WG7
| Descriptor | Carbonic anhydrase 2, Acesulfame, ZINC ION, ... (5 entities in total) |
|---|---|
| Functional Keywords | carbonic anhydrase, acesulfame, inhibitor, lyase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm P00918 |
| Total number of polymer chains | 1 |
| Total molecular weight | 30253.24 |
| Authors | Murray, A.B.,Lomelino, C.L.,Supuran, C.T.,McKenna, R. (deposition date: 2017-07-13, release date: 2018-02-07, Last modification date: 2018-02-21) |
| Primary citation | Murray, A.B.,Lomelino, C.L.,Supuran, C.T.,McKenna, R. "Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms. J. Med. Chem., 61:1176-1181, 2018 PubMed: 29266943 (PDB entries with the same primary citation) DOI: 10.1021/acs.jmedchem.7b01470  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
