5WDK
A processive dipeptidyl aminopeptidase secreted from an established commensal bacterium P. distasonis
Summary for 5WDK
| Entry DOI | 10.2210/pdb5wdk/pdb |
| Descriptor | Aminopeptidase C, POTASSIUM ION, 5-[(3aS,4R,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-oxopropyl)pentanamide, ... (4 entities in total) |
| Functional Keywords | protease, hydrolase |
| Biological source | Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) |
| Total number of polymer chains | 6 |
| Total formula weight | 277598.61 |
| Authors | Wolan, D.W.,Xu, J.H.,Solania, A.,Chatterjee, S.,Jiang, Z.,ODonoghue, A.J. (deposition date: 2017-07-05, release date: 2018-07-11, Last modification date: 2023-10-04) |
| Primary citation | Xu, J.H.,Jiang, Z.,Solania, A.,Chatterjee, S.,Suzuki, B.,Lietz, C.B.,Hook, V.Y.H.,O'Donoghue, A.J.,Wolan, D.W. A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. Acs Chem.Biol., 13:2513-2521, 2018 Cited by PubMed: 30085657DOI: 10.1021/acschembio.8b00420 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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