5W6O

Choline Kinase Alpha in Complex with TCD-717

Summary for 5W6O

• Entry DOI: 10.2210/pdb5w6o/pdb
• Descriptor: Choline kinase alpha, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(methylene)]bis{4-[(4-chlorophenyl)(methyl)amino]quinolin-1-ium}, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: enzyme, inhibitor, drug, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 91002.00

Authors

Kall, S.K.,Lavie, A. (deposition date: 2017-06-16, release date: 2018-02-14, Last modification date: 2019-12-11)

• Primary citation: Kall, S.L.,Delikatny, E.J.,Lavie, A.; Identification of a Unique Inhibitor-Binding Site on Choline Kinase alpha.; Biochemistry, 57:1316-1325, 2018; PubMed: 29389115; DOI: 10.1021/acs.biochem.7b01257

Experimental method

X-RAY DIFFRACTION (2.35 Å)