5W10

Lcd1 GAF domain in complex with cAMP ligand

Summary for 5W10

Entry DOI	10.2210/pdb5w10/pdb
Descriptor	cGMP-specific phosphodiesterase, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	gaf domain, camp binding domain, effector domain, regulates the dgc activity of the ggdef domain, hydrolase
Biological source	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Total number of polymer chains	4
Total formula weight	90266.92
Authors	Guzzo, C.R.,Maciel, N.K.,Barbosa, A.S.,Farah, C.S. (deposition date: 2017-06-01, release date: 2017-06-28, Last modification date: 2020-01-01)
Primary citation	da Costa Vasconcelos, F.N.,Maciel, N.K.,Favaro, D.C.,de Oliveira, L.C.,Barbosa, A.S.,Salinas, R.K.,de Souza, R.F.,Farah, C.S.,Guzzo, C.R. Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species. J. Mol. Biol., 429:2337-2352, 2017 Cited by PubMed: 28601495 DOI: 10.1016/j.jmb.2017.06.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation