5W10

Lcd1 GAF domain in complex with cAMP ligand

5W10 の概要

• エントリーDOI: 10.2210/pdb5w10/pdb
• 分子名称: cGMP-specific phosphodiesterase, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: gaf domain, camp binding domain, effector domain, regulates the dgc activity of the ggdef domain, hydrolase
• 由来する生物種: Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 90266.92

構造登録者

Guzzo, C.R.,Maciel, N.K.,Barbosa, A.S.,Farah, C.S. (登録日: 2017-06-01, 公開日: 2017-06-28, 最終更新日: 2020-01-01)

• 主引用文献: da Costa Vasconcelos, F.N.,Maciel, N.K.,Favaro, D.C.,de Oliveira, L.C.,Barbosa, A.S.,Salinas, R.K.,de Souza, R.F.,Farah, C.S.,Guzzo, C.R.; Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species.; J. Mol. Biol., 429:2337-2352, 2017; PubMed: 28601495; DOI: 10.1016/j.jmb.2017.06.002

実験手法

X-RAY DIFFRACTION (2.15 Å)