5VZ8
Post-catalytic complex of human Polymerase Mu (G433A) mutant with incoming UTP
Summary for 5VZ8
Entry DOI | 10.2210/pdb5vz8/pdb |
Related | 5TWP 5TWQ 5TWR 5TWS |
Descriptor | DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), DNA/RNA (5'-D(*CP*GP*TP*A)-R(P*U)-3'), ... (10 entities in total) |
Functional Keywords | family x, nonhomologous end-joining, dna double strand break repair, ribonucleotide incorporation, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46268.06 |
Authors | Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. (deposition date: 2017-05-27, release date: 2017-07-05, Last modification date: 2023-10-04) |
Primary citation | Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45:9138-9148, 2017 Cited by PubMed: 28911097DOI: 10.1093/nar/gkx527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.601 Å) |
Structure validation
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