5VXZ

High-affinity AXL decoy receptor

5VXZ の概要

• エントリーDOI: 10.2210/pdb5vxz/pdb
• 分子名称: Growth arrest-specific protein 6, Tyrosine-protein kinase receptor UFO, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: engineered decoy receptor, human cancers, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 111257.46

構造登録者

Mathrews, I.I.,Kapur, S.,Kariolis, M.S.,Cochran, J.R. (登録日: 2017-05-24, 公開日: 2017-06-21, 最終更新日: 2023-10-04)

• 主引用文献: Kariolis, M.S.,Miao, Y.R.,Diep, A.,Nash, S.E.,Olcina, M.M.,Jiang, D.,Jones, D.S.,Kapur, S.,Mathews, I.I.,Koong, A.C.,Rankin, E.B.,Cochran, J.R.,Giaccia, A.J.; Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.; J. Clin. Invest., 127:183-198, 2017; PubMed: 27893463; DOI: 10.1172/JCI85610

実験手法

X-RAY DIFFRACTION (2.3 Å)