5VS0

Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 80 s

Summary for 5VS0

• Entry DOI: 10.2210/pdb5vs0/pdb
• Related: 5VRX 5VRY 5VRZ 5VS1 5VS2 5VS3 5VS4
• Descriptor: DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3'), ... (9 entities in total)
• Functional Keywords: 8-oxoguanine, polymerase, ber, transferase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 49304.73

Authors

Reed, A.J.,Suo, Z. (deposition date: 2017-05-11, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Reed, A.J.,Suo, Z.; Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta.; J. Am. Chem. Soc., 139:9684-9690, 2017; PubMed: 28682600; DOI: 10.1021/jacs.7b05048

Experimental method

X-RAY DIFFRACTION (2.1 Å)