5VO3

Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)

Summary for 5VO3

Entry DOI	10.2210/pdb5vo3/pdb
Descriptor	Succinyl-diaminopimelate desuccinylase, SUCCINIC ACID, 2,6-DIAMINOPIMELIC ACID, ... (5 entities in total)
Functional Keywords	dape, hydrolaze, succinic acid, diaminopimelic acid, m28, structural genomics, psi-biology, hydrolase
Biological source	Haemophilus influenzae
Total number of polymer chains	1
Total formula weight	42093.31
Authors	Nocek, B. (deposition date: 2017-05-01, release date: 2018-07-25, Last modification date: 2023-11-15)
Primary citation	Nocek, B.,Reidl, C.,Starus, A.,Heath, T.,Bienvenue, D.,Osipiuk, J.,Jedrzejczak, R.,Joachimiak, A.,Becker, D.P.,Holz, R.C. Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism. Biochemistry, 57:574-584, 2018 Cited by PubMed: 29272107 DOI: 10.1021/acs.biochem.7b01151 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.954 Å)

Structure validation