5VO3
Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009014 | molecular_function | succinyl-diaminopimelate desuccinylase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050897 | molecular_function | cobalt ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue SIN A 501 |
| Chain | Residue |
| A | ASP100 |
| A | HIS349 |
| A | API502 |
| A | ZN503 |
| A | ZN504 |
| A | HOH678 |
| A | GLU134 |
| A | GLU135 |
| A | GLU163 |
| A | ARG178 |
| A | HIS194 |
| A | TYR197 |
| A | GLY324 |
| A | THR325 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue API A 502 |
| Chain | Residue |
| A | GLU134 |
| A | GLU135 |
| A | ALA136 |
| A | SER181 |
| A | HIS194 |
| A | ASN244 |
| A | ASN245 |
| A | ARG258 |
| A | SER290 |
| A | GLY324 |
| A | THR325 |
| A | SIN501 |
| A | HOH698 |
| A | HOH703 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 503 |
| Chain | Residue |
| A | HIS67 |
| A | ASP100 |
| A | GLU163 |
| A | SIN501 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 504 |
| Chain | Residue |
| A | ASP100 |
| A | GLU135 |
| A | HIS349 |
| A | SIN501 |
Functional Information from PROSITE/UniProt
| site_id | PS00758 |
| Number of Residues | 10 |
| Details | ARGE_DAPE_CPG2_1 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. IAFAGHtDVV |
| Chain | Residue | Details |
| A | ILE62-VAL71 |
| site_id | PS00759 |
| Number of Residues | 40 |
| Details | ARGE_DAPE_CPG2_2 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. AADmKGslAamIvaaeeyvkanpnhkgt.IaLLItsDEEaT |
| Chain | Residue | Details |
| A | ALA98-THR137 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20138056","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"20138056","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20138056","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ISZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20138056","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
