5VLO

The structure of human CamKII with bound inhibitor

Summary for 5VLO

• Entry DOI: 10.2210/pdb5vlo/pdb
• Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit delta, N-[(2S)-2-(diethylamino)propyl]-2-[(2S)-2-(methylcarbamoyl)azetidin-1-yl]-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (4 entities in total)
• Functional Keywords: kinase, camkii, inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side : Q13557
• Total number of polymer chains: 2
• Total formula weight: 70321.02

Authors

Somoza, J.R.,Villasenor, A.G. (deposition date: 2017-04-25, release date: 2017-08-23, Last modification date: 2024-03-13)

• Primary citation: Somoza, T.J.,Villasenor, A.G.; Inhibitors of CamKII; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)