5VLO
The structure of human CamKII with bound inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calcium/calmodulin-dependent protein kinase type II subunit delta | polymer | 302 | 34459.6 | 2 | UniProt (Q13557) Pfam (PF00069) | Homo sapiens (Human) | CaMK-II subunit delta |
| 2 | C, E (A, B) | N-[(2S)-2-(diethylamino)propyl]-2-[(2S)-2-(methylcarbamoyl)azetidin-1-yl]-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | non-polymer | 546.7 | 2 | Chemie (9EJ) | |||
| 3 | D, F (A, B) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 2 | Chemie (DTT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 301 (UniProt: Q13557)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| His 1 | - | expression tag |
| Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68919.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1401.9 | |
| All* | Total formula weight | 70321.0 |
