5VHE

DHX36 in complex with the c-Myc G-quadruplex

Summary for 5VHE

• Entry DOI: 10.2210/pdb5vhe/pdb
• Related: 5VHA 5VHC 5VHD
• Descriptor: DEAH (Asp-Glu-Ala-His) box polypeptide 36, DNA (5'-D(*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*TP*TP*TP*TP*T)-3'), POTASSIUM ION (3 entities in total)
• Functional Keywords: hydrolase
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 2
• Total formula weight: 114833.84

Authors

Chen, M.,Ferre-D'Amare, A. (deposition date: 2017-04-13, release date: 2018-06-13, Last modification date: 2023-10-04)

• Primary citation: Chen, M.C.,Tippana, R.,Demeshkina, N.A.,Murat, P.,Balasubramanian, S.,Myong, S.,Ferre-D'Amare, A.R.; Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.; Nature, 558:465-469, 2018; PubMed: 29899445; DOI: 10.1038/s41586-018-0209-9

Experimental method

X-RAY DIFFRACTION (3.793 Å)