5VGB
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
Summary for 5VGB
Entry DOI | 10.2210/pdb5vgb/pdb |
Descriptor | CRISPR-associated endonuclease Cas9, Anti-CRISPR protein (AcrIIC1), GLYCEROL, ... (5 entities in total) |
Functional Keywords | protein, rna, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Neisseria meningitidis More |
Total number of polymer chains | 2 |
Total formula weight | 26816.00 |
Authors | Harrington, L.B.,Doxzen, K.W.,Ma, E.,Knott, G.J.,Kranzusch, P.J.,Doudna, J.A. (deposition date: 2017-04-10, release date: 2017-08-30, Last modification date: 2024-03-13) |
Primary citation | Harrington, L.B.,Doxzen, K.W.,Ma, E.,Liu, J.J.,Knott, G.J.,Edraki, A.,Garcia, B.,Amrani, N.,Chen, J.S.,Cofsky, J.C.,Kranzusch, P.J.,Sontheimer, E.J.,Davidson, A.R.,Maxwell, K.L.,Doudna, J.A. A Broad-Spectrum Inhibitor of CRISPR-Cas9. Cell, 170:1224-1233.e15, 2017 Cited by PubMed: 28844692DOI: 10.1016/j.cell.2017.07.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.497 Å) |
Structure validation
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