5VEZ

DNA polymerase beta substrate complex with 8-oxoG:A at the primer terminus and incoming dCTP analog

Summary for 5VEZ

• Entry DOI: 10.2210/pdb5vez/pdb
• Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total)
• Functional Keywords: transferase ligase / dna, transferase-dna, ligase-dna complex, transferase/dna, ligase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 48306.35

Authors

Freudenthal, B.D.,Schaich, M.A.,Whitaker, A.M.,Smith, M.R. (deposition date: 2017-04-06, release date: 2017-05-10, Last modification date: 2023-10-04)

• Primary citation: Whitaker, A.M.,Smith, M.R.,Schaich, M.A.,Freudenthal, B.D.; Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.; Nucleic Acids Res., 45:6934-6944, 2017; PubMed: 28449123; DOI: 10.1093/nar/gkx293

Experimental method

X-RAY DIFFRACTION (2.039 Å)