5VAX

Bcl-2 complex with Beclin 1 BH3 domain

Summary for 5VAX

• Entry DOI: 10.2210/pdb5vax/pdb
• Related: 5VAU 5VAY 5VB1 5VB4
• Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1 (3 entities in total)
• Functional Keywords: apoptosis, bcl-2, autophagy, beclin 1
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion outer membrane ; Single-pass membrane protein : P10415; Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : Q14457
• Total number of polymer chains: 8
• Total formula weight: 89883.47

Authors

Lee, E.F.,Smith, B.J.,Yao, S.,Fairlie, W.D. (deposition date: 2017-03-28, release date: 2018-04-04, Last modification date: 2023-10-04)

• Primary citation: Lee, E.F.,Smith, B.J.,Yao, S.,Fairlie, W.D.; Bcl-2 complex with Beclin 1 pT108 BH3 domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)