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5VAX

Bcl-2 complex with Beclin 1 BH3 domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, B, C, D)
Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimerapolymer16819545.74UniProt (P10415)
Pfam (PF02180)
Pfam (PF00452)
Homo sapiens (Human)Bcl2-L-1,Apoptosis regulator Bcl-X
2B, D, F, H
(E, F, G, H)
Beclin-1polymer262925.24UniProt (Q14457)
Pfam (PF15285)
Homo sapiensCoiled-coil myosin-like BCL2-interacting protein,Protein GT197
3I, J, K, L, M...
(A, E, B, F, C...)
waterwater18.076Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 75 (UniProt: P10415)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Asp 73Ala 32conflict
A, B, C, D: 76 - 91 (PDB: 5VAX)
A, B, C, D: 92 - 207 (UniProt: P10415)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight89883.5
All*Total formula weight89883.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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