5VAH

Crystal structure of ATXR5 SET domain in complex with histone H3 di-methylated on R26

5VAH の概要

• エントリーDOI: 10.2210/pdb5vah/pdb
• 関連するPDBエントリー: 5VAB 5VAC
• 分子名称: Probable Histone-lysine N-methyltransferase ATXR5, Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: histone, nucleosome, methyltransferases, transferase-dna binding protein complex, transferase/dna binding protein
• 由来する生物種: Ricinus communis (Castor bean); 詳細
• 細胞内の位置: Plastid, chloroplast : B9RU15; Nucleus : P59226
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56037.54

構造登録者

Bergamin, E.,Sarvan, S.,Malette, J.,Eram, M.,Yeung, S.,Mongeon, V.,Joshi, M.,Brunzelle, J.S.,Michaels, S.D.,Blais, A.,Vedadi, M.,Couture, J.-F. (登録日: 2017-03-26, 公開日: 2017-04-05, 最終更新日: 2023-11-15)

• 主引用文献: Bergamin, E.,Sarvan, S.,Malette, J.,Eram, M.S.,Yeung, S.,Mongeon, V.,Joshi, M.,Brunzelle, J.S.,Michaels, S.D.,Blais, A.,Vedadi, M.,Couture, J.F.; Molecular basis for the methylation specificity of ATXR5 for histone H3.; Nucleic Acids Res., 45:6375-6387, 2017; PubMed: 28383693; DOI: 10.1093/nar/gkx224

実験手法

X-RAY DIFFRACTION (2.4 Å)