5V7P

Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody

5V7P の概要

• エントリーDOI: 10.2210/pdb5v7p/pdb
• 分子名称: Protein-S-isoprenylcysteine O-methyltransferase, monobody, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total)
• 機能のキーワード: membrane protein, membrane enzyme, methyltransferase, lcp, transferase
• 由来する生物種: Tribolium castaneum (Red flour beetle); 詳細
• 細胞内の位置: Endoplasmic reticulum membrane ; Multi-pass membrane protein : D6WJ77
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48976.35

構造登録者

Long, S.B.,Diver, M.M.,Pedi, L.,Koide, A.,Koide, S. (登録日: 2017-03-20, 公開日: 2018-01-17, 最終更新日: 2024-03-06)

• 主引用文献: Diver, M.M.,Pedi, L.,Koide, A.,Koide, S.,Long, S.B.; Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.; Nature, 553:526-529, 2018; PubMed: 29342140; DOI: 10.1038/nature25439

実験手法

X-RAY DIFFRACTION (2.3 Å)