5V6L
Crystal Structure of Rabbit Anti-HIV-1 gp120 V3 Fab 10A37 in complex with V3 peptide JR-FL
Summary for 5V6L
Entry DOI | 10.2210/pdb5v6l/pdb |
Related | 5V6M |
Descriptor | Light chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A37, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A37, Envelope glycoprotein, v3 region, ... (4 entities in total) |
Functional Keywords | hiv, gp120, v3, antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Oryctolagus cuniculus (rabbit) More |
Total number of polymer chains | 6 |
Total formula weight | 96561.44 |
Authors | Pan, R.,Kong, X.-P. (deposition date: 2017-03-17, release date: 2018-01-17, Last modification date: 2023-10-04) |
Primary citation | Pan, R.,Qin, Y.,Banasik, M.,Lees, W.,Shepherd, A.J.,Cho, M.W.,Kong, X.P. Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120. J. Virol., 2018 Cited by PubMed: 29343576DOI: 10.1128/JVI.01894-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.549 Å) |
Structure validation
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