5V4I

Osmium(II)(cymene)(chlorido)2-lysozyme adduct with one binding site

Summary for 5V4I

• Entry DOI: 10.2210/pdb5v4i/pdb
• Related: 5V4G 5V4H
• Descriptor: Lysozyme C, SODIUM ION, dichloro[(1,2,3,4,5,6-eta)-3-methyl-6-(propan-2-yl)benzene-1,2,4,5-tetrayl]osmium, ... (4 entities in total)
• Functional Keywords: metal-based, anticancer, osmium, lysozyme, hydrolase
• Biological source: Gallus gallus (Chicken)
• Cellular location: Secreted: P00698
• Total number of polymer chains: 1
• Total formula weight: 14745.47

Authors

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (deposition date: 2017-03-09, release date: 2017-04-05, Last modification date: 2023-10-04)

• Primary citation: Sullivan, M.P.,Groessl, M.,Meier, S.M.,Kingston, R.L.,Goldstone, D.C.,Hartinger, C.G.; The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography.; Chem. Commun. (Camb.), 53:4246-4249, 2017; PubMed: 28361137; DOI: 10.1039/c6cc10150j

Experimental method

X-RAY DIFFRACTION (1.5 Å)