5V4I

Osmium(II)(cymene)(chlorido)2-lysozyme adduct with one binding site

Summary for 5V4I
Related5V4G 5V4H
DescriptorLysozyme C, SODIUM ION, dichloro[(1,2,3,4,5,6-eta)-3-methyl-6-(propan-2-yl)benzene-1,2,4,5-tetrayl]osmium, ... (4 entities in total)
Functional Keywordsmetal-based, anticancer, osmium, lysozyme, hydrolase
Biological sourceGallus gallus (Chicken)
Cellular locationSecreted: P00698
Total number of polymer chains1
Total formula weight14745.47
Authors
Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (deposition date: 2017-03-09, release date: 2017-04-05, Last modification date: 2017-04-19)
Primary citationGoldstone, D.C.,Groessl, M.,Hartinger, C.G.,Kingston, R.L.,Meier, S.M.,Sullivan, M.P.
The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography.
Chem. Commun. (Camb.), 53:4246-4249, 2017
PubMed: 28361137
DOI: 110.1039/c6cc10150j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation
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PDB entries from 2021-06-16