5V4H

Ruthenium(II)(cymene)(chlorido)2-lysozyme adduct formed when ruthenium(II)(cymene)(bromido)2 underwent ligand exchange, resulting in one binding site

Summary for 5V4H

Entry DOI	10.2210/pdb5v4h/pdb
Related	5V4G 5V4I
Descriptor	Lysozyme C, SODIUM ION, PARA-CYMENE RUTHENIUM CHLORIDE, ... (4 entities in total)
Functional Keywords	metal-based, anticancer, ruthenium, lysozyme, hydrolase
Biological source	Gallus gallus (Chicken)
Cellular location	Secreted: P00698
Total number of polymer chains	1
Total formula weight	14660.34
Authors	Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (deposition date: 2017-03-09, release date: 2017-04-05, Last modification date: 2023-10-04)
Primary citation	Sullivan, M.P.,Groessl, M.,Meier, S.M.,Kingston, R.L.,Goldstone, D.C.,Hartinger, C.G. The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography. Chem. Commun. (Camb.), 53:4246-4249, 2017 Cited by PubMed: 28361137 DOI: 10.1039/c6cc10150j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation