5V2Q

CaV beta2a subunit: CaV1.2 AID-CEN complex

Summary for 5V2Q

• Entry DOI: 10.2210/pdb5v2q/pdb
• Related: 5V2P
• Descriptor: Voltage-dependent L-type calcium channel subunit beta-2,Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent L-type calcium channel subunit alpha-1C, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: ion channel, signaling, calcium, transport protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 2
• Total formula weight: 41540.35

Authors

Findeisen, F.,Campiglio, M.,Jo, H.,Rumpf, C.H.,Pope, L.,Flucher, B.,Degrado, W.F.,Minor, D.L. (deposition date: 2017-03-06, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Findeisen, F.,Campiglio, M.,Jo, H.,Abderemane-Ali, F.,Rumpf, C.H.,Pope, L.,Rossen, N.D.,Flucher, B.E.,DeGrado, W.F.,Minor, D.L.; Stapled Voltage-Gated Calcium Channel (CaV) alpha-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of CaV Function.; ACS Chem Neurosci, 8:1313-1326, 2017; PubMed: 28278376; DOI: 10.1021/acschemneuro.6b00454

Experimental method

X-RAY DIFFRACTION (1.7 Å)