5V2Q

CaV beta2a subunit: CaV1.2 AID-CEN complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Voltage-dependent L-type calcium channel subunit beta-2,Voltage-dependent L-type calcium channel subunit beta-2	polymer	346	39099.6	1	UniProt (Q8VGC3) Pfam (PF12052) Pfam (PF00625)	Rattus norvegicus (Rat)	CAB2, Calcium channel voltage-dependent subunit beta 2
2	B (B)	Voltage-dependent L-type calcium channel subunit alpha-1C	polymer	19	2141.4	1	UniProt (Q13936)	Homo sapiens	Calcium channel, L type,alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2
3	C (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	D (B)	1,3-bis(bromomethyl)benzene	non-polymer		264.0	1	Chemie (8VY)
5	E, F (A, B)	water	water		18.0	457	Chemie (HOH)

Sequence modifications

A: 68 - 252 (UniProt: Q8VGC3)
A: 254 - 476 (UniProt: Q8VGC3)

PDB	External Database	Details
Ser 253	-	linker

B: 427 - 445 (UniProt: Q13936)

PDB	External Database	Details
Ala 427	Lys 427	engineered mutation
Ser 428	Gln 428	engineered mutation
Pro 429	Gln 429	engineered mutation
Cys 435	Lys 435	engineered mutation
Cys 439	Asp 439	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41240.9
Non-Polymers*	Number of molecules	2
	Total formula weight	299.4
All*	Total formula weight	41540.3

*Water molecules are not included.