5UZ9

Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex

5UZ9 の概要

• エントリーDOI: 10.2210/pdb5uz9/pdb
• EMDBエントリー: 8624
• 分子名称: CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... (7 entities in total)
• 機能のキーワード: crispr rna-recognition-motif (rrm), pseudo-helical, type 1-f crispr, immune system-rna complex, immune system/rna
• 由来する生物種: Pseudomonas aeruginosa (strain UCBPP-PA14); 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 379215.91

構造登録者

Chowdhury, S.,Carter, J.,Rollins, M.F.,Jackson, R.N.,Hoffmann, C.,Nosaka, L.,Bondy-Denomy, J.,Maxwell, K.L.,Davidson, A.R.,Fischer, E.R.,Lander, G.C.,Wiedenheft, B. (登録日: 2017-02-25, 公開日: 2017-04-26, 最終更新日: 2024-03-13)

• 主引用文献: Chowdhury, S.,Carter, J.,Rollins, M.F.,Golden, S.M.,Jackson, R.N.,Hoffmann, C.,Nosaka, L.,Bondy-Denomy, J.,Maxwell, K.L.,Davidson, A.R.,Fischer, E.R.,Lander, G.C.,Wiedenheft, B.; Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.; Cell, 169:47-57.e11, 2017; PubMed: 28340349; DOI: 10.1016/j.cell.2017.03.012

実験手法

ELECTRON MICROSCOPY (3.4 Å)