5UYY

Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine

5UYY の概要

• エントリーDOI: 10.2210/pdb5uyy/pdb
• 関連するPDBエントリー: 5USC
• 分子名称: Prephenate dehydrogenase, TYROSINE (3 entities in total)
• 機能のキーワード: prephenate dehydrogenase, tyra, bacillus anthracis, csgid, structural genomics, center for structural genomics of infectious diseases, oxidoreductase
• 由来する生物種: Bacillus anthracis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 171555.85

構造登録者

Shabalin, I.G.,Hou, J.,Cymborowski, M.T.,Kwon, K.,Christendat, D.,Gritsunov, A.O.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2017-02-24, 公開日: 2017-03-08, 最終更新日: 2023-10-04)

• 主引用文献: Shabalin, I.G.,Gritsunov, A.,Hou, J.,Slawek, J.,Miks, C.D.,Cooper, D.R.,Minor, W.,Christendat, D.; Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.; Febs J., 287:2235-2255, 2020; PubMed: 31750992; DOI: 10.1111/febs.15150

実験手法

X-RAY DIFFRACTION (2.6 Å)