5UTJ
Crystal Structure of TGT in complex with 2,6-dioxy-8-azapurine, 2,6-dioxy-8-azapurine, 2,6-dioxy-8-azapurine
Summary for 5UTJ
Entry DOI | 10.2210/pdb5utj/pdb |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | tgt, trna, guanine exchange enzyme, transglycosylase, fragments, transferase |
Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Total number of polymer chains | 1 |
Total formula weight | 42272.36 |
Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-02-15, release date: 2018-03-07, Last modification date: 2024-01-17) |
Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.549 Å) |
Structure validation
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