5URY

Crystal structure of Frizzled 5 CRD in complex with PAM

Summary for 5URY

Entry DOI	10.2210/pdb5ury/pdb
Descriptor	Frizzled-5, alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOLEIC ACID, ... (4 entities in total)
Functional Keywords	frizzled 5, crd, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	34706.66
Authors	Mukund, S.,Nile, A.H.,Stanger, K.,Hannoush, R.N.,Wang, W. (deposition date: 2017-02-13, release date: 2017-05-10, Last modification date: 2020-07-29)
Primary citation	Nile, A.H.,Mukund, S.,Stanger, K.,Wang, W.,Hannoush, R.N. Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114:4147-4152, 2017 Cited by PubMed: 28377511 DOI: 10.1073/pnas.1618293114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.098 Å)

Structure validation