5UN6
Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Summary for 5UN6
Entry DOI | 10.2210/pdb5un6/pdb |
Related | 5UN5 |
Descriptor | Frizzled-8, Designed Wnt agonist B12 (2 entities in total) |
Functional Keywords | signaling protein-de novo protein complex, signaling protein/de novo protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 115144.47 |
Authors | Janda, C.Y.,Garcia, K.C.,Jude, K.M. (deposition date: 2017-01-30, release date: 2017-05-03, Last modification date: 2023-10-04) |
Primary citation | Janda, C.Y.,Dang, L.T.,You, C.,Chang, J.,de Lau, W.,Zhong, Z.A.,Yan, K.S.,Marecic, O.,Siepe, D.,Li, X.,Moody, J.D.,Williams, B.O.,Clevers, H.,Piehler, J.,Baker, D.,Kuo, C.J.,Garcia, K.C. Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling. Nature, 545:234-237, 2017 Cited by PubMed: 28467818DOI: 10.1038/nature22306 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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