5UN6
Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G, H (A, B, C, D) | Frizzled-8 | polymer | 129 | 14961.1 | 4 | UniProt (Q9H461) Pfam (PF01392) | Homo sapiens (Human) | hFz8 |
| 2 | B, C, D, E (E, F, G, H) | Designed Wnt agonist B12 | polymer | 123 | 13825.0 | 4 | synthetic construct |
Sequence modifications
A, B, C, D: 1 - 123 (UniProt: Q9H461)
| PDB | External Database | Details |
|---|---|---|
| Gln 22 | Asn 49 | engineered mutation |
| His 124 | - | expression tag |
| His 125 | - | expression tag |
| His 126 | - | expression tag |
| His 127 | - | expression tag |
| His 128 | - | expression tag |
| His 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 115144.5 | |
| All* | Total formula weight | 115144.5 |
