5UN6

Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Frizzled-8	polymer	129	14961.1	4	UniProt (Q9H461) Pfam (PF01392) In PDB	Homo sapiens (Human)	hFz8
2	E, F, G, H	Designed Wnt agonist B12	polymer	123	13825.0	4		synthetic construct

Sequence modifications

A, B, C, D: 1 - 123 (UniProt: Q9H461)

PDB	External Database	Details
Gln 22	Asn 49	engineered mutation
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	115144.5
All*	Total formula weight	115144.5

*Water molecules are not included.