5UN1
Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor
Summary for 5UN1
Entry DOI | 10.2210/pdb5un1/pdb |
Descriptor | N-methyl-D-aspartate receptor subunit NR1-3a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ... (9 entities in total) |
Functional Keywords | complex, arrangement, channel blocker, membrane proteins-inhibitor complex, membrane proteins/inhibitor |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Cell membrane ; Multi- pass membrane protein : A7XY94 |
Total number of polymer chains | 8 |
Total formula weight | 408395.75 |
Authors | Song, X.,Gouaux, E. (deposition date: 2017-01-30, release date: 2018-02-07, Last modification date: 2023-10-04) |
Primary citation | Song, X.,Jensen, M.O.,Jogini, V.,Stein, R.A.,Lee, C.H.,Mchaourab, H.S.,Shaw, D.E.,Gouaux, E. Mechanism of NMDA receptor channel block by MK-801 and memantine. Nature, 556:515-519, 2018 Cited by PubMed: 29670280DOI: 10.1038/s41586-018-0039-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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