5UN1

Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor

5UN1 の概要

• エントリーDOI: 10.2210/pdb5un1/pdb
• 分子名称: N-methyl-D-aspartate receptor subunit NR1-3a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ... (9 entities in total)
• 機能のキーワード: complex, arrangement, channel blocker, membrane proteins-inhibitor complex, membrane proteins/inhibitor
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : A7XY94
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 408395.75

構造登録者

Song, X.,Gouaux, E. (登録日: 2017-01-30, 公開日: 2018-02-07, 最終更新日: 2023-10-04)

• 主引用文献: Song, X.,Jensen, M.O.,Jogini, V.,Stein, R.A.,Lee, C.H.,Mchaourab, H.S.,Shaw, D.E.,Gouaux, E.; Mechanism of NMDA receptor channel block by MK-801 and memantine.; Nature, 556:515-519, 2018; PubMed: 29670280; DOI: 10.1038/s41586-018-0039-9

実験手法

X-RAY DIFFRACTION (3.6 Å)