5U81

Acid ceramidase (ASAH1, aCDase) from naked mole rat, Cys143Ala, uncleaved

5U81 の概要

• エントリーDOI: 10.2210/pdb5u81/pdb
• 関連するPDBエントリー: 5U7Z 5U84
• 分子名称: Acid ceramidase isoform b, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: ceramidase, ceramide, ntn-hydrolase, hydrolase
• 由来する生物種: Heterocephalus glaber (Naked mole rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47237.30

構造登録者

Gebai, A.,Gorelik, A.,Illes, K.,Nagar, B. (登録日: 2016-12-13, 公開日: 2018-03-28, 最終更新日: 2020-07-29)

• 主引用文献: Gebai, A.,Gorelik, A.,Li, Z.,Illes, K.,Nagar, B.; Structural basis for the activation of acid ceramidase.; Nat Commun, 9:1621-1621, 2018; PubMed: 29692406; DOI: 10.1038/s41467-018-03844-2

実験手法

X-RAY DIFFRACTION (1.4 Å)