5U66
Modified single helix from the B-domain of protein A bound to IgG1 Fc
Summary for 5U66
Entry DOI | 10.2210/pdb5u66/pdb |
Related PRD ID | PRD_002261 |
Descriptor | STAPLED PEPTIDE FROM DOMAIN B OF PROTEIN A, IgG1 fc derived from CD4-fc fusion, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | igg1 fc, staple peptide, protein a, b-domain, immune system-inhibitor complex, immune system/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 26896.14 |
Authors | Ultsch, M.H.,Eigenbrot, C. (deposition date: 2016-12-07, release date: 2017-05-24, Last modification date: 2023-11-15) |
Primary citation | Ultsch, M.,Braisted, A.,Maun, H.R.,Eigenbrot, C. 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng. Des. Sel., 30:619-625, 2017 Cited by PubMed: 28475752DOI: 10.1093/protein/gzx029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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