5U2H

Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598

5U2H の概要

• エントリーDOI: 10.2210/pdb5u2h/pdb
• 関連するPDBエントリー: 5U1L 5U1U 5U1V 5U1W 5U1X 5U1Y
• 分子名称: P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-cyano-N'-[(1R)-1-phenylethyl]-N''-quinolin-5-ylguanidine, ... (5 entities in total)
• 機能のキーワード: membrane protein: atp-gated ion channel: agonist and allosteric antagonist bound: closed state, membrane protein
• 由来する生物種: Ailuropoda melanoleuca (Giant panda)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79640.40

構造登録者

Karasawa, A.,Kawate, T. (登録日: 2016-11-30, 公開日: 2017-01-04, 最終更新日: 2024-04-03)

• 主引用文献: Karasawa, A.,Kawate, T.; Structural basis for subtype-specific inhibition of the P2X7 receptor.; Elife, 5:-, 2016; PubMed: 27935479; DOI: 10.7554/eLife.22153

実験手法

X-RAY DIFFRACTION (3.903 Å)