5TYJ

alpha-esterase-7 in complex with (3-bromo-5-phenoxylphenyl)boronic acid

Summary for 5TYJ

Entry DOI	10.2210/pdb5tyj/pdb
Descriptor	Carboxylic ester hydrolase, (3-bromo-5-phenoxyphenyl)boronic acid (3 entities in total)
Functional Keywords	carboxylesterase, insecticide resistance, covalent inhibitor, organophosphate, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Lucilia cuprina (Green bottle fly)
Total number of polymer chains	1
Total formula weight	66739.80
Authors	Correy, G.J.,Jackson, C.J. (deposition date: 2016-11-20, release date: 2017-12-06, Last modification date: 2023-10-04)
Primary citation	Correy, G.J.,Zaidman, D.,Harmelin, A.,Carvalho, S.,Mabbitt, P.D.,Calaora, V.,James, P.J.,Kotze, A.C.,Jackson, C.J.,London, N. Overcoming insecticide resistance through computational inhibitor design. Proc.Natl.Acad.Sci.USA, 116:21012-21021, 2019 Cited by PubMed: 31575743 DOI: 10.1073/pnas.1909130116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation