5TPH

Crystal structure of a de novo designed protein homodimer with curved beta-sheet

Summary for 5TPH

Entry DOI	10.2210/pdb5tph/pdb
Related	5TPJ
Descriptor	de novo NTF2 homodimer, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	de novo ntf2, de novo protein
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	28970.76
Authors	Basanta, B.,Marcos, E.,Oberdorfer, G.,Chidyausiku, T.M.,Sankaran, B.,Baker, D. (deposition date: 2016-10-20, release date: 2017-01-25, Last modification date: 2024-03-06)
Primary citation	Marcos, E.,Basanta, B.,Chidyausiku, T.M.,Tang, Y.,Oberdorfer, G.,Liu, G.,Swapna, G.V.,Guan, R.,Silva, D.A.,Dou, J.,Pereira, J.H.,Xiao, R.,Sankaran, B.,Zwart, P.H.,Montelione, G.T.,Baker, D. Principles for designing proteins with cavities formed by curved beta sheets. Science, 355:201-206, 2017 Cited by PubMed: 28082595 DOI: 10.1126/science.aah7389 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.47 Å)

Structure validation