5THI

Crystal Structure of 2-hydroxycyclohepta-2,4,6-trien-1-one bound to human carbonic anhydrase 2 L198G

Summary for 5THI

Entry DOI	10.2210/pdb5thi/pdb
Related	5TH4 5THJ 5THN 5TI0
Descriptor	Carbonic anhydrase 2, ZINC ION, 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, ... (7 entities in total)
Functional Keywords	carbonic anhydrase 2, complex, metalloenzyme inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	30118.50
Authors	Dick, B.,Cohen, S. (deposition date: 2016-09-29, release date: 2017-04-26, Last modification date: 2023-10-04)
Primary citation	Dick, B.L.,Patel, A.,McCammon, J.A.,Cohen, S.M. Effect of donor atom identity on metal-binding pharmacophore coordination. J. Biol. Inorg. Chem., 22:605-613, 2017 Cited by PubMed: 28389830 DOI: 10.1007/s00775-017-1454-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation