5TGZ
Crystal Structure of the Human Cannabinoid Receptor CB1
Summary for 5TGZ
Entry DOI | 10.2210/pdb5tgz/pdb |
Descriptor | Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, FLAVIN MONONUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | membrane protein, g protein-coupled receptor, human cannabinoid receptor cb1, marijuana, stabilizing antagonist am6538, lipidic cubic phase, cb1-flavodoxin chimera, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 52646.18 |
Authors | Hua, T.,Vemuri, K.,Pu, M.,Qu, L.,Han, G.W.,Wu, Y.,Zhao, S.,Shui, W.,Li, S.,Korde, A.,Laprairie, R.B.,Stahl, E.L.,Ho, J.H.,Zvonok, N.,Zhou, H.,Kufareva, I.,Wu, B.,Zhao, Q.,Hanson, M.A.,Bohn, L.M.,Makriyannis, A.,Stevens, R.C.,Liu, Z.J. (deposition date: 2016-09-28, release date: 2016-11-02, Last modification date: 2023-11-08) |
Primary citation | Hua, T.,Vemuri, K.,Pu, M.,Qu, L.,Han, G.W.,Wu, Y.,Zhao, S.,Shui, W.,Li, S.,Korde, A.,Laprairie, R.B.,Stahl, E.L.,Ho, J.H.,Zvonok, N.,Zhou, H.,Kufareva, I.,Wu, B.,Zhao, Q.,Hanson, M.A.,Bohn, L.M.,Makriyannis, A.,Stevens, R.C.,Liu, Z.J. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell, 167:750-762.e14, 2016 Cited by PubMed: 27768894DOI: 10.1016/j.cell.2016.10.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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