5TGZ

Crystal Structure of the Human Cannabinoid Receptor CB1

5TGZ の概要

• エントリーDOI: 10.2210/pdb5tgz/pdb
• 分子名称: Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, FLAVIN MONONUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: membrane protein, g protein-coupled receptor, human cannabinoid receptor cb1, marijuana, stabilizing antagonist am6538, lipidic cubic phase, cb1-flavodoxin chimera, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52646.18

構造登録者

Hua, T.,Vemuri, K.,Pu, M.,Qu, L.,Han, G.W.,Wu, Y.,Zhao, S.,Shui, W.,Li, S.,Korde, A.,Laprairie, R.B.,Stahl, E.L.,Ho, J.H.,Zvonok, N.,Zhou, H.,Kufareva, I.,Wu, B.,Zhao, Q.,Hanson, M.A.,Bohn, L.M.,Makriyannis, A.,Stevens, R.C.,Liu, Z.J. (登録日: 2016-09-28, 公開日: 2016-11-02, 最終更新日: 2023-11-08)

• 主引用文献: Hua, T.,Vemuri, K.,Pu, M.,Qu, L.,Han, G.W.,Wu, Y.,Zhao, S.,Shui, W.,Li, S.,Korde, A.,Laprairie, R.B.,Stahl, E.L.,Ho, J.H.,Zvonok, N.,Zhou, H.,Kufareva, I.,Wu, B.,Zhao, Q.,Hanson, M.A.,Bohn, L.M.,Makriyannis, A.,Stevens, R.C.,Liu, Z.J.; Crystal Structure of the Human Cannabinoid Receptor CB1.; Cell, 167:750-762.e14, 2016; PubMed: 27768894; DOI: 10.1016/j.cell.2016.10.004

実験手法

X-RAY DIFFRACTION (2.8 Å)